High-throughput-compatible assays using a genetically-encoded calcium indicator.

Measurement of intracellular calcium in live cells is a key component of a wide range of basic life scienceresearch, and crucial for many high-throughput assays used in modern drug discovery. Synthetic calcium indicators have become the industry standard, due their ease of use, high reliability, wide dynamic range, and availability of a large variety of spectral and chemical properties.

Genetically-encoded calcium indicators (GECIs) have been optimized to the point where their performance rivals that of synthetic calcium indicators in many applications. Stable expression of a GECI has distinct advantages over synthetic calcium indicators in terms of reagent cost and simplification of the assay process.

Cortisol EIA Kit

EK7119 96wells/kit
EUR 478.00

Cortisol EIA Kit

SKT-201-96 1 plate of 96 wells
EUR 329.00
  • Cortisol, C21H30O5, (hydrocortisone, compound F) is the primary glucocorticoid produced and secreted by the adrenal cortex. It is often referred to as the ?stress hormone? as it is involved in the response to stress and it affects blood pressure, blo
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Description: Competitive EIA kit used for quantitative measuring cortisol present in Dried Fecal Samples, Saliva, Urine, Serum, EDTA Plasma, Heparin Plasma, Tissue Culture Media samples from all species

Corticosterone EIA Kit

SKT-205-96 1 plate of 96 wells
EUR 355.00
  • Corticosterone (C21H30O4, Kendall's Compound ?B') is a glucocorticoid secreted by the cortex of the adrenal gland. Corticosterone is produced in response to stimulation of the adrenal cortex by ACTH and is the precursor of aldosterone. Corticosterone
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Description: Sandwich EIA kit used to measure the corticosterone present in Serum, EDTA Plasma, Heparin Plasma, Urine, Tissue Culture Media, Dried Fecal Samples samples from all species

Prostaglandin E2 EIA Kit

SKT-207-96 1 plate of 96 wells
EUR 527.00
  • Eicosanoid signal transduction pathways are highly conserved and are involved in a number of physiological processes. Prostaglandins are synthesized from arachidonic acid by cyclooxygenase (COX)-1 or -2, which convert the acid into PGH2. This is furt
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Description: Sandwich EIA kit used for quantitative measuring PGE2 present in Saliva, Urine, Serum, EDTA Plasma, Heparin Plasma, Tissue Culture Media samples from all species

Cyclic AMP EIA Kit

SKT-209-96 1 plate of 96 wells
EUR 454.00
  • Adenosine-3',5'-cyclic monophosphate (cyclic AMP) is a second messenger that plays an important role in intracellular regulation. Specifically, it functions as a mediator of activity of several key hormones including epinephrine, glucagon, and ACTH (
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Description: Direct EIA kit used for quantitative measuring cAMP present in Cell Lysates, Tissue, Saliva, Urine, EDTA Plasma, Heparin Plasma, Tissue Culture Media samples from all species

Cyclic GMP EIA Kit

SKT-211-96 1 plate of 96 wells
EUR 474.00
  • Guanosine 3', 5'-cyclic monophosphate (cyclic GMP
  • cGMP) is a critical and multifunctional second messenger present at levels typically 10-100 fold lower than cAMP in most tissues. Intracellular cGMP is formed by the action of the enzyme guanylate cy
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Description: Direct EIA kit used for quantitative measuring cGMP present in Cell Lysates, Tissue, Saliva, Urine, EDTA Plasma, Tissue Culture Media samples from all species

Cystatin C EIA Kit

SKT-219-96 1 plate of 96 wells
EUR 494.00
  • Cystatin C is a non-glycosylated protein of low molecular weight (13kDa) in the cystatin superfamily. Cystatin C is produced at a constant rate in all nucleated cells, secreted from cells and thus found in detectable amounts in most body fluids (1,2)
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Description: Sandwich EIA kit used to measure cystatin C levels in Serum, EDTA Plasma, Heparin Plasma, Urine, Tissue Culture Media samples from Human

DM1 ADC EIA Kit

DEIABL311 96T Ask for price
Description: This test kit is intended for use in the quantitative determination of antibody-DM1-conjugate level in test sample. It is useful for preclinical and clinical pharmacology study of DM1 Antibody Drug Conjugate (ADC). - Samples from tissue/cell culture a

MMAE ADC EIA Kit

DEIABL312 96T Ask for price
Description: This test kit is intended for use in the quantitative determination of antibody-MMAE-conjugate level in test sample. It is useful for preclinical and clinical pharmacology study of MMAE Antibody Drug Conjugate (ADC). - Samples from tissue/cell culture

MMAF ADC EIA Kit

DEIABL313 96T Ask for price
Description: This test kit is intended for use in the quantitative determination of antibody-MMAF-conjugate level in test sample. It is useful for preclinical and clinical pharmacology study of MMAF Antibody Drug Conjugate (ADC). - Samples from tissue/cell culture

Androstenedione ELISA Kit (Competitive EIA)

EK7019 96wells/kit, with removable strips.
EUR 688.00

Progesterone EIA kit (One Plate)

K025-H1 1x96 well plate
EUR 305.00

Progesterone EIA kit (Five Plates)

K025-H5 5x96 well plate
EUR 1012.00

Estradiol EIA kit (One Plate)

K030-H1 1x96 well plate
EUR 283.00

Estradiol EIA kit (Five Plates)

K030-H5 5x96 well plate
EUR 985.00

Epiandrosterone EIA Kit (Five Plate)

K063-H5 5x96 well plate
EUR 1545.00

Estriol EIA Kit (One Plate)

K064-H1 1x96 well plate
EUR 327.00

Estriol EIA Kit (Five Plate)

K064-H5 5x96 well plate
EUR 1110.00

Epiandrosterone EIA Kit (One Plate)

K063-H1 1x96 well plate
EUR 436.00

Aldosterone EIA Kit (One Plate)

K052-H1 1x96 well plate
EUR 387.00

Aldosterone EIA Kit (Five Plate)

K052-H5 5x96 well plate
EUR 1355.00

Oxytocin EIA Kit (One Plate)

K048-H1 1x96 well plate
EUR 450.00

Oxytocin EIA Kit (Five Plate)

K048-H5 5x96 well plate
EUR 1597.00

Allopregnanolone EIA Kit (One Plate)

K044-H1 1x96 well plate
EUR 425.00

Allopregnanolone EIA Kit (Five Plate)

K044-H5 5x96 well plate
EUR 1490.00

Testosterone EIA kit (One Plate)

K032-H1 1x96 well plate
EUR 316.00

Testosterone EIA kit (Five Plates)

K032-H5 5x96 well plate
EUR 1045.00

Insulin EIA Kit (One Plate)

K046-H1 1x96 well plate
EUR 501.00

Estrone EIA kit (One Plate)

K031-H1 1x96 well plate
EUR 300.00

Estrone EIA kit (Five Plates)

K031-H5 5x96 well plate
EUR 1001.00

Prolactin EIA kit (One Plate)

K040-H1 1x96 well plate
EUR 471.00

EIA Wash Buffer 10x concentrate

1003-1 1 Liter
EUR 231.00

ImmunoComb Chlamydia Bivalent EIA kit

50416002 1 kit
EUR 370.60
Description: Please check the datasheet of ImmunoComb Chlamydia Bivalent EIA kit before using the test.

Human Cotinine ELISA Kit (Competitive EIA)

EK7035 96wells/kit, with removable strips.
EUR 478.00

Human Opiates ELISA Kit (Competitive EIA)

EK7078 96wells/kit, with removable strips.
EUR 478.00

DetectX® Allopregnanolone EIA Antibody, 13ML

C226-13ML 13ML
EUR 1059.00

DetectX® Allopregnanolone EIA Antibody, 3ML

C226-3ML 3ML
EUR 298.00

DetectX® Epiandrosterone EIA Antibody, 13ML

C231-13ML 13ML
EUR 1044.00

DetectX® Epiandrosterone EIA Antibody, 3ML

C231-3ML 3ML
EUR 298.00

Progesterone Metabolites EIA Kit (One Plate)

K068-H1 1x96 well plate
EUR 305.00

Progesterone Metabolites EIA Kit (Five Plate)

K068-H5 5x96 well plate
EUR 1012.00

20-Hydroxyecdysone EIA Kit (One Plate)

K066-H1 1x96 well plate
EUR 511.00

20-Hydroxyecdysone EIA Kit (Five Plate)

K066-H5 5x96 well plate
EUR 1953.00

Retinol Binding Protein Serum EIA Kit

K004-H1 1x96 well plate
EUR 318.00

DNA Damage EIA Kit (One Plate)

K059-H1 1x96 well plate
EUR 552.00

DNA Damage EIA Kit (Five Plate)

K059-H5 5x96 well plate
EUR 2074.00

Myeloperoxidase Human EIA Kit (One Plate)

K060-H1 1x96 well plate
EUR 516.00

DHEA-S EIA Kit (One Plate)

K054-H1 1x96 well plate
EUR 403.00

DHEA-S EIA Kit (Five Plate)

K054-H5 5x96 well plate
EUR 1436.00

ST2 Human EIA Kit, 1 Plate

K055-H1 1x96 well plate
EUR 593.00

Levonorgestrel (LNG) EIA Kit (One Plate)

K058-H1 1x96 well plate
EUR 557.00

Levonorgestrel (LNG) EIA Kit (Five Plate)

K058-H5 5x96 well plate
EUR 2080.00

Thyroxine (T4) EIA kit (One Plate)

K050-H1 1x96 well plate
EUR 400.00

Thyroxine (T4) EIA kit (Five Plates)

K050-H5 5x96 well plate
EUR 1394.00

Triiodothyronine (T3) EIA Kit (One Plate)

K056-H1 1x96 well plate
EUR 400.00

Triiodothyronine (T3) EIA Kit (Five Plate)

K056-H5 5x96 well plate
EUR 1394.00

17-Hydroxyprogesterone EIA kit (One Plate)

K053-H1 1x96 well plate
EUR 566.00

17-Hydroxyprogesterone EIA kit (Five Plate)

K053-H5 5x96 well plate
EUR 1980.00

Estradiol Serum EIA kit (One Plate)

KB30-H1 1x96 well plate
EUR 359.00

Estradiol Serum EIA kit (Five Plates)

KB30-H5 5x96 well plate
EUR 1246.00

Glucagon (human/mouse/rat) EIA Kit

K4756-100
EUR 843.00

Obestatin (human/mouse/rat) EIA Kit

K4759-100 100 assays
EUR 789.00
  • Kit components:
Description: Sensitive, Colorimetric Assay

Resistin (human/mouse/rat) EIA Kit

K4767-100 100 assays
EUR 789.00
  • Kit components:
  • Resistin Microplate (Item A) coated with secondary antibody, 96 wells
  • Wash Buffer Concentrate (20x) (Item B)
  • Standard Resistin Peptide (Item C) (10 μl/vial)
  • Anti-Resistin polyclonal antibody (item N) (5 μl/vial)
  • Assay
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Description: Sensitive, Colorimetric Assay

Ghrelin (human, mouse, rat) EIA Kit

K4790-100 100 assays
EUR 789.00
  • Kit components:
  • Ghrelin Microplate (Item A) coated with secondary antibody, 96 wells
  • Wash Buffer Concentrate (20x) (Item B)
  • Lyophilized Standard Ghrelin Peptide (Item C)
  • Lyophilized anti-Ghrelin Polyclonal antibody (Item N)
  • 1 X Assay Dilue
  • Show more
Description: Sensitive, Colorimetric Assay

Retinol Binding Protein Urinary EIA Kit

SKT-218-96 1 plate of 96 wells
EUR 527.00
  • Retinol binding protein (RBP) is from a family of structurally related proteins that bind small hydrophobic molecules such as bile pigments, steroids, odorants, etc (1). RBP is a 21 kDa highly conserved, single-chain glycoprotein, consisting of 182 a
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Description: Sandwich EIA kit used to measure RBP levels in urine samples in Urine samples from Human, Rat, Dog, Monkey

Human Chlamydia pneumoniae IgG EIA Kit

DEIA1726 96T
EUR 1177.00
Description: CD's Chlamydia pneumoniae IgG test is developed for the detection of IgG antibodies specific to Chlamydia pneumoniae in human serum or plasma. The kit is semiquantitative allowing comparison of paired samples. The change of antibody level is an aid fo

Human Chlamydia pneumoniae IgM EIA Kit

DEIA1727 96T
EUR 1177.00
Description: Chlamydia pneumoniae IgM test (DEIA1727) is developed for the detection of IgM antibodies specific to Chlamydia pneumoniae in human serum or plasma. The positive result is an aid for the diagnosis of acute Chlamydia pneumonia infection. The test

ANA IgG Screening ELISA Kit (Direct EIA)

EK7016 96wells/kit, with removable strips.
EUR 478.00

Human Brucella IgG ELISA Kit (Direct EIA)

EK7021 96wells/kit, with removable strips.
EUR 478.00

Human Brucella IgM ELISA Kit (Direct EIA)

EK7022 96wells/kit, with removable strips.
EUR 478.00

Human Cardiolipin IgG ELISA Kit (Direct EIA)

EK7024 96wells/kit, with removable strips.
EUR 478.00

Human Cardiolipin IgA ELISA Kit (Direct EIA)

EK7025 96wells/kit, with removable strips.
EUR 478.00

Human Cardiolipin IgM ELISA Kit (Direct EIA)

EK7026 96wells/kit, with removable strips.
EUR 478.00

Human DHEA-S ELISA Kit (Competitive EIA)

EK7047 96wells/kit, with removable strips.
EUR 478.00

Human Free Testosterone ELISA Kit (Competitive EIA)

EK7057 96wells/kit, with removable strips.
EUR 572.00

Human Morphine Specific ELISA Kit (Competitive EIA)

EK7070 96wells/kit, with removable strips.
EUR 478.00

Human Mumps IgG ELISA Kit (Direct EIA)

EK7073 96wells/kit, with removable strips.
EUR 478.00

Human Mumps IgM ELISA Kit (Direct EIA)

EK7074 96wells/kit, with removable strips.
EUR 478.00

Human Rubella IgG ELISA Kit (Direct EIA)

EK7082 96wells/kit, with removable strips.
EUR 478.00

Human Rubella IgM ELISA Kit (Direct EIA)

EK7083 96wells/kit, with removable strips.
EUR 478.00

Human Toxoplasma IgG ELISA Kit (Direct EIA)

EK7099 96wells/kit, with removable strips.
EUR 478.00

Human Toxoplasma IgA ELISA Kit (Direct EIA)

EK7100 96wells/kit, with removable strips.
EUR 478.00

Human Toxoplasma IgM ELISA Kit (Direct EIA)

EK7101 96wells/kit, with removable strips.
EUR 478.00

Cyclic GMP Direct EIA kit (One Plate)

K020-H1 1x96 well plate
EUR 379.00

Cyclic GMP Direct EIA kit (Five Plate)

K020-H5 5x96 well plate
EUR 1369.00

Osteopontin Human (OPN) EIA kit (One Plate)

K021-H1 1x96 well plate
EUR 511.00

Cyclic AMP Direct EIA Kit (One Plate)

K019-H1 1x96 well plate
EUR 369.00

Cyclic AMP Direct EIA Kit (Five Plate)

K019-H5 5x96 well plate
EUR 1293.00

Direct Cyclic GMP EIA Kit (One Plate)

K065-H1 1x96 well plate
EUR 369.00

Direct Cyclic GMP EIA Kit (Five Plate)

K065-H5 5x96 well plate
EUR 1293.00

PGE2 Multi-Format EIA kit (One Plate)

K051-H1 1x96 well plate
EUR 379.00

PGE2 Multi-Format EIA kit (Five Plate)

K051-H5 5x96 well plate
EUR 1344.00

C-Peptide (human/mouse/rat) EIA Kit

K4757-100
EUR 843.00

Human Cytomegalovirus (CMV) IgG ELISA Kit (Direct EIA)

EK7032 96wells/kit, with removable strips.
EUR 478.00

Human Cytomegalovirus (CMV) IgM ELISA Kit (Direct EIA)

EK7033 96wells/kit, with removable strips.
EUR 478.00

Human Chromogranin A (CgA) ELISA Kit (Direct EIA)

EK7034 96wells/kit, with removable strips.
EUR 688.00

Human Chlamydia Pneumoniae IgA ELISA Kit (Direct EIA)

EK7036 96wells/kit, with removable strips.
EUR 478.00

Human Chlamydia Pneumoniae IgG ELISA Kit (Direct EIA)

EK7037 96wells/kit, with removable strips.
EUR 478.00

Human Chlamydia Pneumoniae IgM ELISA Kit (Direct EIA)

EK7038 96wells/kit, with removable strips.
EUR 478.00

Human Chlamydia Trachomatis IgG ELISA Kit (Direct EIA)

EK7041 96wells/kit, with removable strips.
EUR 478.00

Human Chlamydia Trachomatis IgM ELISA Kit (Direct EIA)

EK7042 96wells/kit, with removable strips.
EUR 478.00

Human Chlamydia Trachomatis IgA ELISA Kit (Direct EIA)

EK7043 96wells/kit, with removable strips.
EUR 478.00

Human Dengue Virus IgG ELISA Kit (Direct EIA)

EK7045 96wells/kit, with removable strips.
EUR 478.00

Human Dengue Virus IgM ELISA Kit (Direct EIA)

EK7046 96wells/kit, with removable strips.
EUR 478.00

Human HSV-1 IgG ELISA Kit (Direct EIA)

EK7058 96wells/kit, with removable strips.
EUR 478.00

Human HSV-1 IgM ELISA Kit (Direct EIA)

EK7059 96wells/kit, with removable strips.
EUR 478.00

Human HSV-2 IgG ELISA Kit (Direct EIA)

EK7060 96wells/kit, with removable strips.
EUR 478.00

Human HSV-2 IgM ELISA Kit (Direct EIA)

EK7061 96wells/kit, with removable strips.
EUR 478.00

Human Mycoplasma Pneumoniae IgG ELISA Kit (Direct EIA)

EK7071 96wells/kit, with removable strips.
EUR 478.00

Human Mycoplasma Pneumoniae IgM ELISA Kit (Direct EIA)

EK7072 96wells/kit, with removable strips.
EUR 478.00

Human Measles (Rubeola) IgG ELISA Kit (Direct EIA)

EK7075 96wells/kit, with removable strips.
EUR 478.00

Human Measles (Rubeola) IgM ELISA Kit (Direct EIA)

EK7076 96wells/kit, with removable strips.
EUR 478.00

Human Mitochondrial Antibody (MA) ELISA Kit (Direct EIA)

EK7077 96wells/kit, with removable strips.
EUR 478.00

Human SSA Autoantibody IgG ELISA Kit (Direct EIA)

EK7085 96wells/kit, with removable strips.
EUR 478.00

Human SSB Autoantibody IgG ELISA Kit (Direct EIA)

EK7086 96wells/kit, with removable strips.
EUR 478.00

Human Sm Autoantibody IgG ELISA Kit (Direct EIA)

EK7088 96wells/kit, with removable strips.
EUR 478.00

Human Salmonella Typhi IgM ELISA Kit (Direct EIA)

EK7089 96wells/kit, with removable strips.
EUR 478.00

Human Salmonella Typhi IgG ELISA Kit (Direct EIA)

EK7090 96wells/kit, with removable strips.
EUR 478.00

Human Thyroglobulin (TG) IgG ELISA Kit (Direct EIA)

EK7091 96wells/kit, with removable strips.
EUR 478.00

Human Treponema Pallidum IgG ELISA Kit (Direct EIA)

EK7095 96wells/kit, with removable strips.
EUR 478.00

Human Treponema Pallidum IgM ELISA Kit (Direct EIA)

EK7096 96wells/kit, with removable strips.
EUR 478.00

Alkaline Phosphatase (Calf, AP) Enzyme, purified EIA grade

ALP15-N-5 5 mg
EUR 286.00

Atrial Natriuretic Peptide (ANP) EIA kit (One Plate)

K026-H1 1x96 well plate
EUR 420.00

Atrial Natriuretic Peptide (ANP) EIA kit (Five Plates)

K026-H5 5x96 well plate
EUR 1394.00

Cyclic AMP Direct Chemiluminescent EIA kit (One Plate)

K019-C1 1x96 well plate
EUR 400.00

Cyclic AMP Direct Chemiluminescent EIA kit (Five Plate)

K019-C5 5x96 well plate
EUR 1471.00

Direct 2'3'-Cylic GAMP EIA Kit, (One Plate)

K067-H1 1x96 well plate
EUR 511.00

Direct 2'3'-Cylic GAMP EIA Kit, (Five Plate)

K067-H5 5x96 well plate
EUR 1953.00

Allopregnanolone EIA Kit, Monoclonal Antibody Based (One Plate)

K061-H1 1x96 well plate
EUR 425.00

Allopregnanolone EIA Kit, Monoclonal Antibody Based (Five Plate)

K061-H5 5x96 well plate
EUR 1490.00

Pregnanediol-3-Glucuronide (PDG) EIA Kit (One Plate)

K037-H1 1x96 well plate
EUR 321.00

Pregnanediol-3-Glucuronide (PDG) EIA Kit (Five Plate)

K037-H5 5x96 well plate
EUR 1061.00

Estrone-3-Sulfate (E1S) EIA Kit (One Plate)

K038-H1 1x96 well plate
EUR 533.00

Estrone-3-Sulfate (E1S) EIA Kit (Five Plate)

K038-H5 5x96 well plate
EUR 1980.00

Estrone-3-Glucuronide (E1G) EIA Kit (One Plate)

K036-H1 1x96 well plate
EUR 327.00

Estrone-3-Glucuronide (E1G) EIA Kit (Five Plate)

K036-H5 5x96 well plate
EUR 1088.00

Endothelin-1 (ET-1) EIA kit (One Plate)

K045-H1 1x96 well plate
EUR 557.00

Anthrax Protective Antigen IgG Screening ELISA Kit (Direct EIA)

EK7017 96wells/kit, with removable strips.
EUR 920.00

Human RNP Sm Autoantibody IgG ELISA Kit (Direct EIA)

EK7084 96wells/kit, with removable strips.
EUR 478.00

Human Scl-70 Autoantibody IgG ELISA Kit (Direct EIA)

EK7087 96wells/kit, with removable strips.
EUR 478.00

Human Thyroid Peroxidase (TPO) IgG ELISA Kit (Direct EIA)

EK7094 96wells/kit, with removable strips.
EUR 478.00

Human 25(OH) Vitamin D ELISA Kit (Competitive EIA)

EK7102 96wells/kit, with removable strips.
EUR 920.00

Human Double Stranded DNA (dsDNA) IgG ELISA Kit (Direct EIA)

EK7044 96wells/kit, with removable strips.
EUR 478.00

Human Helicobacter pylori IgG ELISA Kit (Direct EIA) (H. pylori)

EK7064 96wells/kit, with removable strips.
EUR 478.00

Human Helicobacter pylori IgA ELISA Kit (Direct EIA) (H. pylori)

EK7065 96wells/kit, with removable strips.
EUR 478.00

Human Helicobacter pylori IgM ELISA Kit (Direct EIA) (H. pylori)

EK7066 96wells/kit, with removable strips.
EUR 478.00

Human VZV (Varicella zoster virus) IgG ELISA Kit (Direct EIA)

EK7103 96wells/kit, with removable strips.
EUR 478.00

Human VZV (Varicella zoster virus) IgM ELISA Kit (Direct EIA)

EK7104 96wells/kit, with removable strips.
EUR 478.00

Retinol Binding Protein (RBP) Multi-format EIA Kit (One Plate)

K062-H1 1x96 well plate
EUR 369.00

Retinol Binding Protein (RBP) Multi-format EIA Kit (Five Plate)

K062-H5 5x96 well plate
EUR 1344.00

Retinol Binding Protein High Sensitivity EIA Kit (formerly named Urinary)

KU04-H1 1x96 well plate
EUR 410.00

Retinol Binding Protein High Sensitivity EIA Kit (formerly named Urinary)

KU04-H5 5x96 well plate
EUR 1491.00

Human Cardiolipin Total Ab (IgG, IgM, IgA) ELISA Kit (Direct EIA)

EK7027 96wells/kit, with removable strips.
EUR 478.00

Human EBV-VCA IgG ELISA Kit (Direct EIA) (Epstein-Barr Virus viral capsid antigen)

EK7050 96wells/kit, with removable strips.
EUR 478.00

Human EBV-VCA IgA ELISA Kit (Direct EIA) (Epstein-Barr Virus viral capsid antigen)

EK7051 96wells/kit, with removable strips.
EUR 478.00

Human EBV-VCA IgM ELISA Kit (Direct EIA) (Epstein-Barr Virus viral capsid antigen)

EK7052 96wells/kit, with removable strips.
EUR 478.00

We generated a clonal cell line constitutively expressing GCaMP6s; high expression of the GECI was driven by coupling to a blasticidin resistance gene with a self-cleaving cis-acting hydrolase element (CHYSEL) 2A peptide. Here, we compared the performance of the GECI GCaMP6s to the synthetic calcium indicator fluo-4 in a variety of assay formats. We demonstrate that the pharmacology of ion channel and GPCR ligands as determined using the two indicators is highly similar, and that GCaMP6s is viable as a direct replacement for a synthetic calcium indicator.